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Morphological and chemical authentication were accomplished in accordance with the Chinese Pharmacopoeia [ 22 ] or herbal medicine reference book since no monograph was found in Chinese Pharmacopoeia for Hedyotis diffusa [ 23 ]. Since one of the component herbs within the formula possess potent immuno-stimulating activities, the overall modulatory effects of the formula were further determined. The outcome of herbal formula treatment was the prolong life span of the metastatic breast tumor-bearing mice. When oxygen and nutrients are supplied to the tumor cells, angiogenesis has an important role in the growth, invasion and metastasis for the tumor. In Chinese community, including Hong Kong, many breast cancer patients take traditional Chinese herbal prescriptions as adjuvant treatments. Even though the skills of surgery, radiotherapy and chemotherapy, targeted therapy and immunotherapy have significantly improved, an increasing number of patients are selecting naturopathic therapy with traditional Chinese medicine TCM , as they are considered to be multicomponents and multitarget agents exerting their therapeutic function in a more holistic way to the whole body system via restoration of the normal balance and flow in the body, which is believed to strengthen and enhance the endogenous resistance of the body to disease and individualization of therapy. Received : 01 September
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